The activity and location of cathepsin D inhibitor in seeds of common vetch (Vicia sativa L.).
نویسندگان
چکیده
The activity of cathepsin D inhibitor is markedly higher in common vetch seed coat than in embryo cotyledons. The occurrence of considerable amounts of the inhibitor in the seed coat of vetch was confirmed by the fluorescent microscopic technique, with the use of fluorescein-marked cathepsin D.
منابع مشابه
Effects of cathepsin D inhibitor from Vicia sativa L. seed hulls on human skin fibroblasts and breast cancer cells (in vitro studies).
Cathepsin D is a lysosomal protease which plays an important role in cancer invasion and metastasis. There are known inhibitors of that enzyme, such as pepstatin and potato inhibitor. In this study, we examined effects of the cathepsin D inhibitor from Vicia sativa L. seed hulls on cell cultures of human skin fibroblasts and breast cancer cells. There is no effect of the D-cathepsin inhibitor f...
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ورودعنوان ژورنال:
- Roczniki Akademii Medycznej w Bialymstoku
دوره 49 Suppl 1 شماره
صفحات -
تاریخ انتشار 2004